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American Journal of Alzheimer's Disease and Other Dementias®
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Development and Evaluation of a Computerized Test Battery for Alzheimer's Disease Screening in Community-based Settings

Masashi Inoue, PhD

Information Media Center, Tottori University, Yonago, Japan, masashi{at}med.totttori-u.ac.jp

Daiki Jinbo, MS

Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University, Yonago, Japan

Yuka Nakamura, MS

Department of Biological Regulation, School of Health Science, Faculty of Medicine Tottori University, Yonago, Japan

Miyako Taniguchi, PhD

Department of Biological Regulation, School of Health Science, Faculty of Medicine Tottori University, Yonago, Japan

Katsuya Urakami, MD

Department of Biological Regulation, School of Health Science, Faculty of Medicine Tottori University, Yonago, Japan

Aim. To evaluate the capability of a computerized test battery for Alzheimer's disease screening which has been newly developed to provide a standardized and efficient method for widespread use in routine clinical and community-based settings.

Methods. Participants were 72 individuals diagnosed with Alzheimer's disease and 102 healthy elderly individuals. Both groups were tested by the battery. Receiver operating characteristic analysis was used to examine the ability of the battery to differentiate between those with Alzheimer's disease and cognitively healthy elderly individuals.

Results. On a group level, the Alzheimer's disease group performed worse than the control group on each of the 4 computerized test tasks. Receiver operating characteristic analysis yielded maximum sensitivity and specificity values of 96% and 86% for total scores, respectively.

Conclusion. We believe the battery is very useful for routine clinical and community-based settings.

Key Words: Alzheimer's disease • computer • screening

This version was published on April 1, 2009

American Journal of Alzheimer's Disease and Other Dementias®, Vol. 24, No. 2, 129-135 (2009)
DOI: 10.1177/1533317508330222


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