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The Prevalence of Dementia in an Urban Turkish Population

Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Faculty of Medicine, Istanbul University, Capa, Istanbul, Turkey, gurvit{at}istanbul.edu.tr

M. Emre, MD

Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Faculty of Medicine, Istanbul University, Capa, Istanbul, Turkey

S. Tinaz, MD, PhD

Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Faculty of Medicine, Istanbul University, Capa, Istanbul, Turkey, Department of Neurology, School of Medicine, Boston University, Boston, MA

B. Bilgic, MD

Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Faculty of Medicine, Istanbul University, Capa, Istanbul, Turkey, Department of Neurology, Istanbul Neuropsychiatric Hospital, Umraniye, Istanbul, Turkey

H. Hanagasi, MD

Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Faculty of Medicine, Istanbul University, Capa, Istanbul, Turkey

H. Sahin, MD

Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Faculty of Medicine, Istanbul University, Capa, Istanbul, Turkey, Department of Neurology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey

E. Gurol, MD

Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Faculty of Medicine, Istanbul University, Capa, Istanbul, Turkey, Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA

J.T. Kvaloy, PhD

Department of Mathematics and Natural Sciences, University of Stavanger, Stavanger, Norway

H. Harmanci, MD

Department of Public Health, Faculty of Medicine, Marmara University, Haydarpasa, Istanbul, Turkey

A cross-sectional, population-based, 2-stage prevalence study was conducted in a sample of 1019 community-dwelling persons over the age of 70 years living in Istanbul. In the first phase, participants were screened with the Mini-Mental State Examination for evidence of cognitive impairment. In the second phase, 79% of those who screened positive (n = 322) and 9% of screen-negatives (n = 63) underwent a standardized diagnostic workup. Diagnosis of dementia and Alzheimer's disease (AD) was made according to established criteria. Ninety-three cases of dementia were identified, 58 of whom were diagnosed with probable AD. Based on these numbers, the prevalence rates of probable AD and dementia were calculated to be 11.0% (95% CI, 7.0% to 15.0%) and 20.0% (95% CI, 14.0% to 26.0%), respectively, in this population. Prevalence rates of dementia and AD in Istanbul, Turkey, are comparable with those seen in the Western world.

Key Words: dementia • Alzheimer's disease • epidemiology • prevalence

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