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American Journal of Alzheimer's Disease and Other Dementias®
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Genetic aspects of Alzheimer's disease, Pick's disease, and other dementias

Linda E. Nee, MSW

Family Studies Unit, National Institute of Neurological Disorders and Stroke, Clinical Center, Bethesda, Maryland.neel{at}ninds.nih.gov

Michael C. Tierney, MAM

Cognitive Neuroscience Section, National Institute of Neurological Disorders and Stroke, Clinical Center, Bethesda, Maryland

Carol F. Lippa, MD

Department of Neurology, Drexel University College of Medicine, Philadelphia, Pennsylvania

Although genetic testing is available for some degenerative diseases, in most types of dementia, both genetic and environmental factors are involved. Overall, dementing diseases can be either sporadic or inherited, and in general, the earlier the onset, the more likely a disease is to be inherited. Before genetic testing is performed, the ethical issues, such as the effect the tests might have on asymptomatic children, should be considered. The ethical use of DNA samples in research is another genetic testing issue to be considered.

Key Words: Alzheimer's disease • dementia with Lewy bodies • frontotemporal dementia • genetics • inheritance • prion • Pick's disease

American Journal of Alzheimer's Disease and Other Dementias®, Vol. 19, No. 4, 219-225 (2004)
DOI: 10.1177/153331750401900412
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This article has been cited by other articles:


Home page
 AM J ALZHEIMERS DIS OTHER DEMENHome page
C. F. Lippa
An Individualized Approach to Treatment for Alzheimer's Disease, Pick's Disease, and Other Dementias.
American Journal of Alzheimer's Disease and Other Dementias, October 1, 2006; 21(5): 354 - 359.
[Abstract] [PDF]


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