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American Journal of Alzheimer's Disease and Other Dementias®
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Creutzfeldt-Jakob disease: Two case studies

Clarissa A. Rentz, MSN, RN, CS

Greater Cincinnati Chapter of the Alzheimer's Association, Cincinnati, Ohio.

Creutzfeldt-Jakob disease (CJD) is a rapidly progressive, neurodegenerative disorder causing dramatic neuromuscular symptoms, profound dementia, and death. In this article, the epidemiology, etiology, modes of transmission, clinical manifestations, determination of possible/ probable CJD diagnosis in life, and the postmortem neuropathology of definite CJD are discussed in depth. Case studies of two individuals, each affected by different subtypes of sporadic Creutzfeldt-Jakob disease (sCJD), are presented, along with a discussion of the many challenging nursing and psychosocial issues surrounding the supportive care of these individuals and families in life and death.

Key Words: Creutzfeldt-Jakob disease • nursing care • psychosocial family issues of CJD

American Journal of Alzheimer's Disease and Other Dementias®, Vol. 18, No. 3, 171-180 (2003)
DOI: 10.1177/153331750301800309
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