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American Journal of Alzheimer's Disease and Other Dementias®
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Slowly progressive aphasia with striatal involvement

Nages Nagaratnam, FRACP

Gary Cheuk, FRACP

Kujan Nagaratnam, FRACP

Aged Care Services and Rehabilitation Services (Department of Medicine), Blacktown Mount Druitt Health, Blacktown, New South Wales, Australia

We have described four patients with slowly progressive aphasia with striatal involvement occurring at different stages in the course of the illness. There were two males and two females, and their ages ranged from 68 to 76 (mean: 72) years. The extrapyramidal signs included tremors, bradykinesia, rigidity, and focal dystonia, and one had weakness resembling stroke. There is a heterogeniety among patients with slowly progressive aphasia and the clinical features correspond to the functional anatomy of the areas involved rather than to the pathology.

Key Words: aphasia • bradykinesia • dementia • dystonia • extrapyramidal signs • rigidity • striatal involvement • tremors

American Journal of Alzheimer's Disease and Other Dementias®, Vol. 17, No. 1, 18-22 (2002)
DOI: 10.1177/153331750201700107
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