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American Journal of Alzheimer's Disease and Other Dementias®
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Changes in emotional and behavioral symptoms of Alzheimer's disease

Michelle M. Lee, MA

Milton E. Strauss, PhD

Department of Psychology, Case Western Reserve University and Alzheimer Center, University Hospitals of Cleveland, Cleveland, Ohio

Deborah V. Dawson, PhD

Department of Epidemiology and Biostatistics, School of Medicine, Case Western Reserve University, Cleveland, Ohio

Emotional distress and disruptive behaviors were assessed for 26 persons with Alzheimer's disease (AD) at admission to a research registry and again three years later. Average prevalence of disruptive behaviors increased, as did the variability among patients in these characteristics. Individual differences in disruptive symptoms at initial assessment were unrelated to symptom status three years later. Emotional symptoms decreased on average and the patient group became more homogeneous in this symptom dimension. Nonetheless, individual differences in prevalence showed significant stability over three years. These differences in pattern of average change and predictability of changes suggest the importance of studying behavioral change in Alzheimer's disease in terms of individual differences as well as group trends within specific symptom clusters.

American Journal of Alzheimer's Disease and Other Dementias®, Vol. 15, No. 3, 176-179 (2000)
DOI: 10.1177/153331750001500305


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