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The effects of peripheral tactile stimulation on memory in patients with probable Alzheimer's disease

Institute of Physiotherapy The Netherlands

Anke Bouma, MD, PhD

Departnent of Clinical Psychology, Free University, Amsterdam, The Netherlands

Louis Steen, MD

Centre of Informatics, University of Amsterdam, The Netherlands

The authors investigated whether peripheral tactile nerve stimulation might improve memory in patients with iProbable Alzheimer s disease. The hypothesis was derived from animal studies in which peripheral stimulation resulted in activation of septo-hippocampal neurons. Our data meveal that tactile stimulation improved visual short-term, visual long-!erm, and verbal long-term mem orv in Alzheimer patients. In addition, an enhancement in verbal fluency was demonstrated. After a period of six weeks without stimulation, nio noticeable effects remained.

American Journal of Alzheimer's Disease and Other Dementias®, Vol. 10, No. 3, 15-21 (1995)
DOI: 10.1177/153331759501000304


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